THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
KWONG, PETER,LUSSO, PAOLO,KWON, YOUNG DO,LIU, QINGBO,MASCOLA, JOHN
申请号:
CA3091437
公开号:
CA3091437A1
申请日:
2019.02.21
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Antibodies and antigen binding fragments that specifically bind to HIV-1 Env and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.