John R. Mascola,Rebecca M. Lynch,Xueling Wu,Mark Connors,Tongqing Zhou,Joseph Casazza,Peter D. Kwong
申请号:
US14386920
公开号:
US20150044137A1
申请日:
2013.03.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Neutralizing antibodies that specifically bind to HIV-1 gp120 and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV infection is disclosed.