Useful and pyrrolo pyrimidine derivatives in the treatment of proliferative diseases

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专利权人:

ノバルティス アーゲー

发明人:

ジョルジョ・カラヴァッティ,ペーター・トラクスラー,トーマス・エッサー,ハンダン・ヘ

申请号：

JP2006550122

公开号：

JP4970052B2

申请日:

2005.01.28

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The present invention relates to a compound of formula I wherein R1 is a heterocyclic radical or an unsubstituted or substituted aromatic radical； G is C1-C7-alkylene, -C(-O)-, or C1-C6-alkylene-C(-O)- wherein the carbonyl group is attached to the piperazine moiety； Q is -NH- or -O-, with the proviso that Q is -O- if G is -C(-O)- or C1-C6-alkylene-C(-O)-； and X is either not present or C1-C7-alkylene, with the proviso that a heterocyclic radical R1 is bonded via a ring carbon atom if X is not present； or a salt thereof, which is useful for treating anti-proliferative diseases.

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