A compound of formula (I) or a tautomeric form, regioisomer, stereoisomer, solvate, N-oxide or pharmaceutically acceptable salts thereof； wherein &lsquo；a&rsquo；&mdash；is selected from the group consisting of substituted or unsubstituted heterocycloalkyl ring and substituted or unsubstituted carbohydrate moiety y is a member selected from &mdash；O&mdash；, &mdash；CO&mdash；, &mdash；S02-, aminoalkyl or formula (II) wherein, Rw is hydrogen, substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl； x is a member selected from -0-, &mdash；S&mdash；, &mdash；SO&mdash；, &mdash；S02-, CONR10, NR10CO and &mdash；NRd&mdash；, or x and y together represent a chemical bond； Z is selected from &mdash；CH&mdash；, &mdash；N&mdash；. t is an integer selected from O to 4； with the provisos that when &lsquo；a&rsquo； is substituted or unsubstituted heterocycloalkyl ring then &lsquo；t&rsquo； is not O and when y=&mdash；CO&mdash；, x is not NRd.
