Methods and Composition for Preparation of Orthogonal TRNA-Aminoacyl-TRNA Synthetase Pairs

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专利权人:

THE SCRIPPS RESEARCH INSTITUTE;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人:

SCHULTZ, PETER,WANG, LEI,ANDERSON, JOHN, CHRISTOPHER,CHIN, JASON, W.,MAGLIERY, THOMAS, J.,MEGGERS, ERIC, L.,PASTRNAK, MIRO,SANTORO, STEPHEN, WILLIAM,LIU, DAVID, R.,MEHL, RYAN, AARON,ZHANG, ZHIWEN

申请号：

DK02731454

公开号：

DK1456360T3

申请日:

2002.04.19

申请国别(地区):

DK

年份:

2015

代理人:

摘要：

This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/