THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;THE SCRIPPS RESEARCH INSTITUTE
发明人:
SCHULTZ, PETER,WANG, LEI,ANDERSON, JOHN CHRISTOPHER,CHIN, JASON W.,LIU, DAVID R.,MAGLIERY, THOMAS J.,MEGGERS, ERIC L.,MEHL, RYAN AARON,PASTRNAK, MIRO,SANTORO, STEPHEN WILLIAM,ZHANG, ZHIWEN
申请号:
DK09006800
公开号:
DK2128246T3
申请日:
2002.04.19
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.