Perkinton, Michael,Schofield, Darren,Irving, Lorraine,Thom, George
申请号：
AU2017272804
公开号：
AU2017272804A1
申请日:
2017.06.01
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The invention provides antibodies that specifically bind human Į-synuclein with a high affinity and reduces Į-synuclein spreading in vivo, recombinant polypeptides comprising said antibodies or antigen-binding fragment thereof and methods for generating such polypeptides, as well as compositions and methods for generating Į-synuclein antibodies, and methods of using Į-synuclein antibodies for the treatment of diseases of the central nervous system, in particular alpha-synucleinopathies.
