Darren Schofield,Michael Perkinton,Lorraine Irving,George Thom
申请号：
US15611416
公开号：
US10160800B2
申请日:
2017.06.01
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides antibodies that specifically bind human α-synuclein with a high affinity and reduces α-synuclein spreading in vivo, recombinant polypeptides comprising said antibodies or antigen-binding fragment thereof and methods for generating such polypeptides, as well as compositions and methods for generating α-synuclein antibodies, and methods of using α-synuclein antibodies for the treatment of diseases of the central nervous system, in particular alpha-synucleinopathies.
