ARMANI Elisabetta (IT),АРМАНИ Элизабетта (IT),AMARI Gabriele (IT),АМАРИ Габриэле (IT),CAPALDI Carmelida (IT),КАПАЛЬДИ Кармелида (IT),CARZANIGA Laura (IT),КАРЦАНИГА Лаура (IT),LA PORTA Elena (IT),ЛА ПО,ARMANI Elisabetta,АРМАНИ Элизабетта,AMARI Gabriele,АМАРИ Габриэле,CAPALDI Carmelida,КАПАЛЬДИ Кармелида,CARZANIGA Laura,КАРЦАНИГА Лаура,LA PORTA Elena,ЛА ПОРТА Элена,GUALA Matilde,ГУАЛА Матильде
申请号：
RU2014115290
公开号：
RU0002617401C2
申请日:
2012.10.10
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
FIELD: chemistry.SUBSTANCE: invention relates to compounds of general formula (I) (I), where: R1 and R2, which can be identical or different, independently selected from a group consisting of: - (C1-C6)alkyl, optionally substituted (C3-C7)cycloalkyl； - (C1-C6)halogenalkyl； - (C3-C7)cycloalkyl and - (C3-C7)heterocycloalkyl, containing heteroatom O； R3 represents hydrogen, (C1-C6)alkyl or (C1-C3)alkylthio(C1-C6)alkyl； A is a partially unsaturated or unsaturated bicyclic ring system consisting of two condensed monocyclic ring systems B and C, presented in cl. 1 of formula, where ring C is a monocyclic aryl or monocyclic heteroaryl ring system, ring B is a 5- or 6-member heterocycloalkyl group, zero of Y groups is bonded to ring C, n of groups Y is bonded to ring B, and n is an integer from 1 to 3； and where ring B and C optionally contains additional heteroatoms in amount of 1 to 4, selected from N, O or S； p is an integer from 0 to 3； Y denotes oxo group； K is selected from a group consisting of: - (C1-C6)alkyl, optionally substituted with one (C3-C7)cycloalkyl group； - (C3-C6)heterocycloalkyl(C1-C4)alkyl containing 1 or 2 heteroatoms selected from N or O； - (C3-C6)heterocycloalkyl containing 1 or 2 heteroatoms selected from N or O, optionally substituted with one or more (C1-C6)alkyl group； - (C1-C4)halogenalkyl； - OR4, where R4 selected from a group consisting of: - H； - (C1-C6)alkyl, optionally substituted (C3-C7)cycloalkyl or heteroaryl； - halogen atoms； - CN； - NO2； - NR5R6, where R5 and R6, which can be identical or different, independently selected from a group consisting of: - H； - OH； - (C1-C4)alkyl-NR7R8, where R7 and R8, which can be identical or different, independently selected from a group consisting of: H； (C1-C6)alkyl, possibly substituted (C1-C6)alkoxyl； and (C1-C6)alkyl-NR9R10, where R9 and R10, which can be identical or different, represent H or (C1-C6)alkyl； or they form together with a nitrogen atom to which they are bonded, (C3-C6)heterocycloalk
