PROBLEM TO BE SOLVED: To provide a water-soluble minoxidil composition which is used for the treatment of alopecia and calvities, contains water as a base and contains substantially no organic solvent.SOLUTION: The minoxidil composition for external use includes minoxidil, water, an absorption promoter, and dissolution promoting molecules, and has a water content reaching 95%. The water-soluble minoxidil composition is apparently improved in percutaneous absorption efficiency compared with famous treatments for alopecia, Rogaine or Regaine.COPYRIGHT: (C)2011,JPO&INPIT【課題】 脱毛及び禿頭の治療に用い、組成物が水を基質としており、かつほとんど有機溶剤を含まない、水溶性ミノキシジル組成物の提供。【解決手段】 外用の水溶性ミノキシジル(minoxidil)組成物は、ミノキシジル、水、吸収促進剤、溶解促進分子を含有し、前記組成物中の水分含量が95%に達することができ、有名な脱毛症治療剤ロゲイン(Rogaine;Regaine)と比較すると、水溶性ミノキシジル組成物の経皮吸収効率が明らかに向上される。【選択図】 図1
