A nanohybrid drug carrier prepared by a Pickering emulsion template method with magadiite as an emulsifier and a preparation method therefor. With organic magadiite as the emulsifier and an organic solvent capable of dissolving and dispersing a PLGA as an oil phase, a Pickering drug emulsion is prepared, and then a PLGA-magadiite nanohybrid drug controlled-release carrier is prepared by using a solvent evaporation method.