ODA, Shannon, K.,GREENBERG, Philip, D.,SCHMITT, Thomas, M.
申请号:
SG11201707182W
公开号:
SG11201707182WA
申请日:
2016.03.04
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
The present disclosure relates to immunomodulatory fusion proteins containing an extracellular binding domain and an intracellular signaling domain, wherein binding of a target can generate a modulatory signal in a host cell, such as a T cell. The present disclosure also relates to uses of immune cells expressing such immunomodulatory fusion proteins to treat certain diseases, such as cancer or infectious disease.