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PEPTIDE FOXM1 ET AGENT MEDICINAL LE COMPRENANT
专利权人:
ONCOTHERAPY SCIENCE; INC.
发明人:
NISHIMURA, YASUHARU,YOKOMINE, KAZUNORI,TSUNODA, TAKUYA,NAKAMURA, YUSUKE
申请号:
CA2696597
公开号:
CA2696597C
申请日:
2008.08.12
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
An objective of the present invention is to provide a means for enablingcancer immunotherapy that targets approximately 30% of various cancer patientsthathighly express forkhead box M1 (FOXM1) among the Japanese, by identifyingFOXM1-derived peptides that can activate cancer cell-damaging human killer Tcellsby binding to HLA-A2. The present invention provides a peptide of (A) or (B)below:(A) a peptide including the amino acid sequence of any one of SEQ ID NOs:1 to 3;(B) a peptide which includes the amino acid sequence of any one of SEQ IDNOs: 1 to 3, wherein one, two, or several amino acid(s) are substituted,deleted,inserted, and/or added, and wherein the peptide shows cytotoxic (killer) Tcell-inducing activity.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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