ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
发明人:
CHEN, QIANG,YANG, MING,LAI, HUAFANG
申请号：
CA3065794
公开号：
CA3065794A1
申请日:
2018.05.31
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to the fields of genetically modified Agrobacterium strains, vaccine adjuvants, and generally molecular biology and immunology. Provided herein are modified Agrobacterium strains that produce lipopolysaccharide (LPS) having reduced toxicity or detoxified lipopolysaccharide, and methods of obtaining such strains for plant-based production of biologies. Also provided herein are uses of reduced or detoxified LPS as adjuvants suitable for clinical use.
