Dosage d'oligonucléotides adaptés pour le traitement de tumeurs

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专利权人:

Autotelic LLC

发明人:

申请号：

EP09759924.5

公开号：

EP2356234B1

申请日:

2009.11.13

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

This invention is related to the use of an antisense oligonucleotide, comprising 8 to 30 nucleotide building blocks, which hybridizes with mRNA of TGF-beta 1, -2 and/or -3, VEGF, interleukin 10, c-jun, c-fos, MIA, and/or prostaglandin E2 for the preparation of a pharmaceutical composition for preventing and/or treating a tumor, wherein the antisense oligonucleotide is suitable to be administered intravenously in an amount of 400 to 800 mg/m2/treatment cycle.

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