A usage of composition containing lactobacillus plantarum in regulating lipid metabolism is disclosed, which provides one kind of lactobacillus plantarum that is combined with at least one carbohydrate for a usage of manufacturing a composition to regulate lipid metabolism. By giving an effective quantity of the aforementioned composition to an individual, the cell growth/accumulation of the lipid inside the individual can be prohibited, thereby achieving an efficacy to prevent or treat diseases relating to disorders of lipid metabolism.本發明係揭露一種植物乳桿菌合併至少一醣類用於製造調控脂質代謝之組合物之用途。藉由投予有效量之上述組合物至一個體,其係能抑制該個體體內脂肪細胞生長及/或脂肪細胞累積之情況,進而達到預防或治療與脂肪代謝異常相關病症之功效,