LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND METHOD FOR DELIVERYING NUCLEIC ACID GENE USING THE SAME
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
发明人:
PARK, TAE-GWAN,KIM, HYUN-RYOUNG,KIM, IN-KYOUNG
申请号：
EP08838580
公开号：
EP2217221A4
申请日:
2008.10.17
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
Disclosed are a LDL-like cationic nanoparticle for delivering a nucleic acid gene with improved transfection efficiency and stability, which is surface modified and re-constructed by mimicking lipid components of a natural LDL, a method for preparation of the same, and a method for delivering nucleic acid genes using the same. The cationic nanoparticle of the present invention could effectively be applied in treatment of cancer that overexpress LDL receptors.
