Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies

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专利权人:

ChemoCentryx; Inc.

发明人:

Thomas Schall,James J. Campbell

申请号：

US16740861

公开号：

US10792360B1

申请日:

2020.01.13

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Provided herein are compositions, methods and kits for treating inflammatory bowel disease (IBD) such as Crohn's disease and ulcerative colitis in a mammal in need thereof. The method include administering to a subject with IBD a combination therapy containing a therapeutically effective amount of a chemokine receptor 9 (CCR9) inhibitor compound and a therapeutically effective amount of an anti-TNFα antibody. Also provided herein is a kit containing the CCR9 inhibitor compound and anti-TNFα antibody.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/