Combination therapy of inhibitors of C-C chemokine receptor type 9 (CCR9) and anti-alha4beta7 integrin blocking antibodies

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专利权人:

Inc.;ChemoCentryx

发明人:

Ebsworth, Karen,Wang, Yu,Zeng, Yibin,Zhang, Penglie,Tan, Joanne

申请号：

AU2015328396

公开号：

AU2015328396A1

申请日:

2015.10.05

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Provided herein are compositions, methods and kits for treating inflammatory bowel disease (IBD) such as Crohn's disease and ulcerative colitis in a mammal in need thereof. The method include administering to a subject with IBD a combination therapy containing a therapeutically effective amount of a chemokine receptor 9 (CCR9) inhibitor compound and a therapeutically effective amount of an anti-a4p7 integrin antibody such as vedolizumab. Also provided herein is a kit containing the CCR9 inhibitor compound and anti-a4p7 integrin antibody.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/