COMBINATION THERAPY OF INHIBITORS OF C-C CHEMOKINE RECEPTOR TYPE 9 (CCR9) AND ANTI-ALHA4BETA7 INTEGRIN BLOCKING ANTIBODIES

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专利权人:

INC.;CHEMOCENTRYX

发明人:

EBSWORTH, KAREN,WANG, YU,ZENG, YIBIN,ZHANG, PENGLIE,TAN, JOANNE

申请号：

SG11201702793X

公开号：

SG11201702793XA

申请日:

2015.10.05

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

Provided herein are compositions, methods and kits for treating inflammatory bowel disease (IBD) such as Crohn's disease and ulcerative colitis in a mammal in need thereof. The method include administering to a subject with IBD a combination therapy containing a therapeutically effective amount of a chemokine receptor 9 (CCR9) inhibitor compound and a therapeutically effective amount of an anti-α4β7 integrin antibody such as vedolizumab. Also provided herein is a kit containing the CCR9 inhibitor compound and anti-α4β7 integrin antibody.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/