FIELD: chemistry.SUBSTANCE: invention relates to fluorine-substituted cyclic amino compound of general formula I or a pharmaceutically acceptable salt thereof. Compounds of formula I have acetylcholinesterase inhibitor properties. In formula Igeneral formula Im is an integer equal to 1； n is an integer equal to 0； X is (CH2)p or CO, where p is an integer equal to 1 or 2； R1 is an unsubstituted C3-C10 cycloalkyl or substituted or unsubstituted phenyl； substitute(s) R1 is (are) 1, 2, 3, 4 or 5 identical or different substitutes independently selected from a group consisting of halogen, C1-C6 alkyl, halogen-substituted C1-C6 alkyl, C1-C6 alkoxycarbonyl, halogen-substituted C1-C6 alkoxy, cyano, nitro, phenyl； or two adjacent phenyl substitutes and carbon atom(s) of phenyl together form a 5-member heterocyclic radical, containing 2 heteroatoms selected from O； each of R2 and R3 is independently selected from a group consisting of hydrogen, carboxyl, C1-C4 alkoxycarbonyl and C1-C4 alkyl； or R2 and R3 together form C1-C4 alkylidene； R4 represents 2 substitutes selected from a group consisting of halogen, C1-C6 alkoxy, halogen-substituted C1-C6 alkoxy and -O[(CH2)qO]rR5, where R5 is selected from a group consisting of C1-C6 alkyl； wherein q equals 1； r is equal to 1； said halogen is F, Cl, Br or I. Invention also relates to a method of producing a fluorine-substituted cyclic amino compound, a pharmaceutical composition, acetylcholinesterase inhibitor and use of fluorine-substituted cyclic amino compound to prepare drugs for treating or preventing acetylcholinesterase-associated nervous system diseases.EFFECT: technical result is obtaining novel compounds of fluorine-substituted cyclic amino compound of general formula I, having acetylcholinesterase inhibitor properties.11 cl, 4 tbl, 92 exИзобретение относится к фторзамещенному циклическому аминосоединению общей формулы I или его фармацевтически приемлемой соли. Соединения формулы I обладают свойствами ингибитора ацетилхол
