An implant (95, 600) for treatment of a vascular space can form open loops (612) and closed loops (622) in separate cycles (610, 620) to provide balanced stiffness and flexibility. Such an implant (95, 600) provides both stability for retention within the vascular space and conformability for mitigating forces on the vasculature. Such a configuration can also provide proper coverage over an opening to a vascular space into which the implant (95, 600) is delivered, for reducing or eliminating flow into or out of the body cavity and promoting occlusion of the vascular space.