PURPOSE: A method for preparing white ginseng extract with ginsenoside Rg3 content using acid-hydrolyzing thermal treatment is provided to enhance ginsenoside Rg3 content and to ensure anti-tumor activity. CONSTITUTION: An acid-hydrolyzed white ginseng extract containing ginsenoside Rg3 is prepared by preparing white ginseng extract, performing thermal treatment of the white ginseng extract, and converting white ginseng extract to Rg3. A pharmaceutical composition for anti-tumor activity contains the acid-hydrolyzed white ginseng extract containing ginsenoside Rg3 as an active ingredient. A health food for improving anti-tumor activity contains the acid-hydrolyzed white ginseng extract containing ginsenoside Rg3 as an active ingredient.본 발명은 백삼 추출물을 산가수분해 열처리함으로써 진세노이드 Rg3 함량이 높은 백삼 추출물의 제조 방법과 이로부터 제조된 진세노이드 Rg3 함량이 높은 백삼 추출물에 관한 것을, 본 발명에 따라 제조된 산가수분해 백삼 추출물은 일반 백삼 추출물에 비해 진세노사이드 Rg3 함량이 현저히 높고, 그에 따라 종양 세포주에 대한 항종양 활성이 훨씬 우수한 효과가 있다.
