LAZARIDES, ELIAS,WOODS, CATHERINE,BERNARD, MARK A.
申请号：
HRP20150691
公开号：
HRP20150691T1
申请日:
2015.06.29
申请国别(地区):
HR
年份:
2015
代理人:
摘要：
The invention relates to anti-±2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of ±2 integrin and inhibit the interaction of ±2²1 integrin with collagen. Also disclosed are therapeutic uses of anti-±2 integrin antibodies in treating ±2²1-mediated disorders, including anti-±2 integrin antibodies that bind to ±2 integrin without activating platelets.
