Anti-alpha2 integrin antibodies and their uses

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专利权人:

Glenmark Pharmaceuticals S.A.

发明人:

Lazarides, Elias,Bernard, Mark,Woods, Catherine

申请号：

AU2006315037

公开号：

AU2006315037B2

申请日:

2006.11.17

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The invention relates to anti-α2 integrin antibodies and their uses.Humunized antibodies are disclosed that bind to the I domain of α2 integrinand inhibit the interaction of α2β1 integrin with collagen. Alsodisclosed are therapeutic uses of anti-α2 integrin antibodies in treatingα2β1-mediated disorders, including anti-α2 integrinantibodie s that bind to α2 integrin without activating platelets.

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中国工程科技知识中心

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