A novel Lactobacillus strain has an ability of inhibiting Streptococcus mutans. The present invention provides an Lactobacillus salivarius subsp. salivarius K43, deposited in Bioresource Collection and Research Center under Accession No. BCRC 910616. The present invention also provides a composition comprising the novel Lactobacillus strain. Moreover, the present invention still further provides uses of the novel Lactobacillus strain for the production of the pharmaceutical composition used for prophylaxis or treatment of oral diseases.一種新穎的乳酸桿菌菌株,其具有抑制轉糖鏈球菌作用。本發明揭露一種唾液乳酸桿菌唾液亞種(Lactobacillus salivarius subsp.salivarius)K43,其係寄存於食品工業發展研究所之生物資源保存及研究中心,並取得該中心所給予的登錄號BCRC 910616。本發明亦揭露一種組成物,包括新穎的乳酸桿菌。本發明再進一步提供乳酸桿菌菌株用於製備治療或預防口腔疾病之醫藥組成物的用途。
