AICHER, THOMAS DANIEL,ANZEVENO, PETER BIAGIO,LI, RENHUA,KRASUTSKY, ALEXEI PAVLOVYCH,MABRY, THOMAS EDWARD,SAEED, ASHRAF,SNYDER, NANCY JUNE,STEPHENSON, GREGORY ALAN,TIAN, HONGQI,WALLACE, OWEN BRENDAN,WI
申请号:
CA2647677
公开号:
CA2647677C
申请日:
2007.04.05
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention discloses novel compounds of Formula (I): having 11.beta.-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I), as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11.beta.-HSD type 1 activity.