SEVIGNY, LEILA,BEIL, CHRISTIAN,BRONDYK, WILLIAM H.,CHEN, YANGDE,CHENG, SENG H.,CONNORS, TIMOTHY D.,DEVAUD, CATHERINE,HOFFMANN, DIETMAR,LANGE, CHRISTIAN,MAGNAY, MAUREEN,MAGNAY, TRISTAN,PRADES, CATHERIN
申请号:
CA3053774
公开号:
CA3053774A1
申请日:
2018.02.16
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Provided herein multispecific (e.g., bispecific) binding molecules comprising a first binding domain that binds an extracellular portion of dystroglycan and a second binding domain that binds laminin-2. Further provided herein are methods for making such binding molecules and uses of such binding molecules for treating and/or preventing alpha-dystroglycanopathies.