Christian Beil,William H. Brondyk,Yangde Chen,Seng H. Cheng,Timothy D. Connors,Catherine Devaud,Dietmar Hoffmann,Christian Lange,Maureen Magnay,Tristan Magnay,Catherine Prades,Ercole Rao,Leila Sevigny
申请号：
US15932251
公开号：
US20180237511A1
申请日:
2018.02.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided herein multispecific (e.g., bispecific) binding molecules comprising a first binding domain that binds an extracellular portion of dystroglycan and a second binding domain that binds laminin-2. Further provided herein are methods for making such binding molecules and uses of such binding molecules for treating and/or preventing alpha-dystroglycanopathies.
