Christian BEIL,William H. BRONDYK,Yangde CHEN,Seng H. CHENG,Timothy D. CONNORS,Catherine DEVAUD,Dietmar HOFFMANN,Christian LANGE,Maureen MAGNAY,Tristan MAGNAY,Catherine PRADES,Ercole RAO,Leila SEVIGNY
申请号：
US16818304
公开号：
US20200317761A1
申请日:
2020.03.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein multispecific (e.g., bispecific) binding molecules comprising a first binding domain that binds an extracellular portion of dystroglycan and a second binding domain that binds laminin-2. Further provided herein are methods for making such binding molecules and uses of such binding molecules for treating and/or preventing alpha-dystroglycanopathies.
