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6–[(פירידין–2–יל–מתיל)–אמינו]–h9–פורין–2–יל אמינו אלכוהולים, תהליך להכנתם ותכשירים רפואיים המכילים אותם
专利权人:
CYCLACEL LIMITED
发明人:
申请号:
IL16678305
公开号:
IL166783A
申请日:
2005.02.09
申请国别(地区):
IL
年份:
2013
代理人:
摘要:
The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or un branched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, CNS disorders, diabetes, stroke, alopecia or neurodegenerative disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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