CLARKE, DAVID KIRKWOOD,HENDRY, ROGER MICHAEL,UDEM, STEPHEN A.,PARKS, CHRISTOPHER LEE
申请号:
CA2799469
公开号:
CA2799469C
申请日:
2005.04.05
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV). More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.