CLARKE, DAVID, KIRKWOOD,HENDRY, ROGER, MICHAEL,UDEM, STEPHEN, A.,PARKS, CHRISTOPHER, LEE
申请号:
DK05763601
公开号:
DK1756287T3
申请日:
2005.04.05
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV). More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.