David Kirkwood Clarke;Roger Michael Hendry;Christopher Lee Parks;Stephen A. Udem
发明人:
David Kirkwood Clarke,Roger Michael Hendry,Stephen A. Udem,Christopher Lee Parks
申请号：
US11547236
公开号：
US08287878B2
申请日:
2005.04.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV). More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.
