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Fine particles coated with lipid membrane
专利权人:
Yasuki Kato
发明人:
Yasuki Kato,Masahiro Yamauchi,Hiroko Kusano,Takeshi Iwata,Takaaki Uochi,Shiro Akinaga
申请号:
US12656487
公开号:
US09757344B2
申请日:
2010.02.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A coated fine particle comprisisng: (i) a complex of a drug and a cationic lipid, wherein (a) the drug is a nucleic acid and the complex is obtained by mixing the drug and the cationic lipid in water, wherein the complex has a diameter of 10 nm to 1,000 nm, and (ii) a lipid layer formed of lipid(s), wherein the lipid(s) is selected from phospholipid, glyceroglycolipid, sphingoglycolipid, cholesterol and synthetic lipid, wherein the complex is coated with the lipid layer.
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