CHOI, CHARLES TAK MING,蔡 德明,蔡 德明,SUN, SHU HAI,孙树海,孫樹海,LEE, YI HSUAN,李宜轩,李宜軒
申请号:
TW100135451
公开号:
TWI442905B
申请日:
2011.09.30
申请国别(地区):
TW
年份:
2014
代理人:
摘要:
The present invention provides an apparatus for locating the target of the stimulation, based on both the microelectrode recording (MER) and electrical impedance tomography (EIT) techniques and a hybrid probe is used, the hybrid probe comprising at least one MER sensor and multiple microelectrode contacts. Therefore, after the hybrid probe is inserted in the depth conformed with stimulation target as guided by MER signals, the microelectrode contacts are used and the brain tissue conductivity near the hybrid probe can be profiled. According to the tissue conductivity profile, the precise location of the target of the stimulation and the implant trajectory can be identified. Therefore, the present invention can provide a device and a method for the DBS lead to be implanted into the precise location within the stimulation target with the advantages of faster and more precise target location.本發明係提供一種刺激目標範圍標定裝置,係應用微電極記錄及電阻抗斷層造影技術配合複合式探針,該複合式探針係包含至少一微電極記錄感測器和複數個微電極,以在複合式探針以微電極記錄訊號為導引植入符合刺激目標的深度後,利用該複數個微電極描繪出複合式探針周圍的組織結構,而標定出刺激目標的範圍及植入該複合式探針之精確位置。據此,本案係具有檢測快速、精確等優點,並解決現有深層腦部電刺激技術無法得知精確植入位置的問題。306‧‧‧第一複合式探針308‧‧‧電極310‧‧‧腦部312‧‧‧訊號產生器314‧‧‧訊號接收器