YEUNG, YIK ANDY,FELDMAN, REID MARTIN RENNY,CHU, LING HON MATTHEW,CHAPARRO RIGGERS, JAVIER FERNANDO,DJURETIC, IVANA,MOSYAK, LIDIA,LIN, LAURA
申请号:
CA3034912
公开号:
CA3034912A1
申请日:
2019.02.26
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to human interleukin 15 (IL-15) variants thathavetherapeutic and diagnostic use, and methods for making thereof. The presentinventionalso provides fusion proteins comprising a human IL-15 variant. Also providedaremethods of stimulating or suppressing immune responses in a mammal, andmethodsof treating a disorder (e.g., cancer) using the IL-15 variants or the fusionprotein of suchIL-15 variants.