YEUNG, Yik Andy,FELDMAN, Reid Martin Renny,CHU, Ling Hon Matthew,CHAPARRO RIGGERS, Javier Fernando,DJURETIC, Ivana,LIN, Laura,MOSYAK, Lidia
申请号:
AU2019228381
公开号:
AU2019228381A1
申请日:
2019.02.26
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention relates to human interleukin 15 (IL-15) variants that have therapeutic and diagnostic use, and methods for making thereof. The present invention also provides fusion proteins comprising a human IL-15 variant. Also provided are methods of stimulating or suppressing immune responses in a mammal, and methods of treating a disorder (e.g., cancer) using the IL-15 variants or the fusion protein of such IL-15 variants.