Yik Andy Yeung,Reid Martin Renny Feldman,Ling Hon Matthew Chu,Javier Fernando Chaparro Riggers,Ivana Djuretic,Laura Lin,Lidia Mosyak
申请号：
US16286158
公开号：
US20190263877A1
申请日:
2019.02.26
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to human interleukin 15 (IL-15) variants that have therapeutic and diagnostic use, and methods for making thereof. The present invention also provides fusion proteins comprising a human IL-15 variant. Also provided are methods of stimulating or suppressing immune responses in a mammal, and methods of treating a disorder (e.g., cancer) using the IL-15 variants or the fusion protein of such IL-15 variants.
