Increasing the Sensitivity of Gas Chromatography and Gas Chromatography-Mass Spectrometry Analysis By Allowing Relatively Large Solvent Volume Injections While Reducing Sample Loss And System Contamination
The disclosure is related to preparing a sample for chemical analysis by evaporating at least a portion of solvent included in the sample. After depositing the sample into a sample container, in some examples, at least a portion of the solvent can be evaporated. Solvent evaporation can be achieved at room temperature, at an elevated temperature, at atmospheric pressure, or by drawing a vacuum in the sample container, for example. The one or more compounds of interest can pass through a sample delivery port on the sample container into the chemical analysis device for analysis, for example. Preliminary reduction or elimination of the solvent can increase the overall amount of compounds of interest delivered into the chemical analysis device, for example. In some examples, when extra sensitivity may not be needed, less solvent can be used, which can result in a greener analytical technique that is better for the environment.
