Lentiviral vector-based Japanese encephalitis immunogenic composition

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专利权人:

Centre National de la Recherche Scientifique;Institut Pasteur

发明人:

Charneau, Pierre,Despres, Philippe,De Wispelaere, Melissanne,Souque, Philippe,Frenkiel, Marie-Pascale

申请号：

AU2015359525

公开号：

AU2015359525A1

申请日:

2015.12.07

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention relates to a lentiviral vector-based Japanese encephalitis (JE) immunogenic composition. The present invention is directed to a recombinant lentiviral vector expressing the precursor of membrane (prM) and the envelope (E) protein, in particular glycoprotein of a Japanese encephalitis virus (JEV) or immunogenic fragments thereof. The present invention also provides cells expressing the lentiviral vector, uses and methods to prevent a JEV infection in a mammalian host, especially in a human or an animal host, in particular a pig or a piglet, preferably a domestic pig or a domestic piglet.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/