CHARNEAU PIERRE,DESPRES PHILIPPE,DE WISPELAERE MELISSANNE,SOUQUE PHILIPPE,FRENKIEL MARIE PASCALE
申请号:
IN201717018476
公开号:
IN201717018476A
申请日:
2017.05.25
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention relates to a lentiviral vector based Japanese encephalitis (JE) immunogenic composition. The present invention is directed to a recombinant lentiviral vector expressing the precursor of membrane (prM) and the envelope (E) protein in particular glycoprotein of a Japanese encephalitis virus (JEV) or immunogenic fragments thereof. The present invention also provides cells expressing the lentiviral vector uses and methods to prevent a JEV infection in a mammalian host especially in a human or an animal host in particular a pig or a piglet preferably a domestic pig or a domestic piglet.