KOUWEN, ROELOF HENDRIK MATTHIJS,VAN HEE, PIM,VAN SINDEREN, DOUWE,MCDONNELL, BRIAN,MAHONY, JENNIFER
申请号：
CA2939053
公开号：
CA2939053A1
申请日:
2015.02.20
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Bacteriophage Insensitive Mutants (BIMs) of three Streptococcus thermophilus parent strains were generated and characterized for phage sensitivity, sedimentation rate, cell chain length, phage adsorption and CRISPR locialterations. Several BIMs showed an altered sedimentation phenotype as well as an increase cell chain length, reduced phage sensitivity, reduced phage adsorption and 100% identity in three CRISPR loci. The results show that the derived BIMs have become phage-resistant through a mechanism other than CRISPR.
