SMITH, ROGER ASTBURY,KETHIRI, RAGHAVA REDDY,KRISTAM, RAJENDRA,LAPING, NICHOLAS JAMES,VENKATESHAPPA, CHANDREGOWDA,KULKARNI, BHEEMASHANKAR,DEVRAJ, RAJESH,DEWANG, PURUSHOTTAM,VENKATESAN, ARANPAKAM
申请号：
CA2850551
公开号：
CA2850551A1
申请日:
2012.09.28
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present application provides novel pyridine compounds and pharmaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP 17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CPY17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.
