Roger Astbury Smith,Nicholas James Laping,Aranapakam Venkatesan,Scott Kevin Thompson,Raghava Reddy Kethiri,Dhanalakshmi Sivanandhan,Chandregowda Venkateshappa,Bheemashankar Kulkarni,Purushottam Dewang
申请号：
US13632007
公开号：
US20130085164A1
申请日:
2012.09.30
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present application provides novel imidazole compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CPY17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.
