Roger Astbury Smith,Nicholas James Laping,Aranapakam M. Venkatesan,Raghava Reddy Kethiri,Chandregowda Venkateshappa,Bheemashankar Kulkarni,Purushottam Dewang,Rajendra Kristam,Rajesh Devraj
申请号：
US13632006
公开号：
US08809372B2
申请日:
2012.09.30
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present application provides novel pyridine compounds and pharmaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CYP17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.
