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METHODS FOR TREATING CHRONIC PAIN
专利权人:
ПФАЙЗЕР ЛИМИТЕД (GB)
发明人:
КОРРАДИНИ Лаура (GB),МАЧИН Айан (GB),ПОУЛСЕН Кристиан Тодд (US),ШЕЛТОН Дэвид Льюис (US),ЦЕЛЛЕР Йорг (US)
申请号:
RU2010136969/10
公开号:
RU2010136969A
申请日:
2009.03.03
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. The use of an anti-CGRP antagonistic antibody for the manufacture of a medicament for the prevention and / or treatment of chronic pain and / or symptoms of chronic pain. ! 2. The use according to claim 1, where the drug is prepared for administration peripherally. ! 3. The use according to claim 1, where the drug is administered peripherally. ! 4. The use according to claim 1, where the drug is prepared for administration orally, sublingually, for administration by inhalation, transdermally, subcutaneously, intravenously, intraarterially, intraarticularly, periarticularly, topically and / or intramuscularly. ! 5. The use according to claim 4, wherein the drug is prepared for administration subcutaneously or intravenously. ! 6. The use according to claim 1, where the anti-CGRP antagonistic antibody when administered acts peripherally. ! 7. The use according to claim 1, where the chronic pain includes one or more of chronic nociceptive pain, chronic neuropathic pain, chronic inflammatory pain, fibromyalgia, periodic pain and persistent pain. ! 8. The use of claim 7, wherein the chronic pain further includes one or more of hyperplasia, allodynia, central sensitization, peripheral sensitization, disinhibition, and enhanced signaling. ! 9. The use according to claim 1, where the chronic pain is pain associated with cancer. ! 10. The use according to claim 9, where the pain associated with cancer is pain caused by one of the following pathological conditions: adenocarcinoma in the glandular tissue, blastoma in the embryonic tissue of the organs, carcinoma in the epithelial tissue, leukemia in the tissue that forms blood cells, lymphoma1. Применение анти-CGRP антагонистического антитела для производства лекарственного средства для предотвращения и/или лечения хронической боли и/или симптомов хронической боли. ! 2. Применение по п.1, где лекарственное средство готовят для введения периферически. ! 3. Применение по п.1, где лекарственное средство вводят периферически.
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