MOHAMMED ASMAL,ALES MEDEK,RANDAL BYRN,STEVEN JONES,SIMON ADAM O'NEIL,PRAVEEN MUDUNURI,JOHN GREGG VAN ALSTEN,MICHAEL WALDO,MARK WILLEM LEDEBOER,KWAME W. NTI-ADDAE,DAINIUS MACIKENAS,YI SHI,VALDAS JURKAU
申请号:
PT14802787
公开号:
PT3068776T
申请日:
2014.11.12
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula:are Form A of HCl salt of Compound(1)·1/2H<;sub>;2<;/sub>;O, Form F of HCl salt of Compound(1)·3H<;sub>;2<;/sub>;O, Form D of HCl salt of Compound(1),Form A of Compound(1),and Form A of tosylate salt of Compound(1).Such polymorphic forms are employed for treating influenza, inhibiting the replication of influenza viruses, or reducing the amount of influenza viruses in a biological sample or in a subject.