SEO JEONG HUN,서정훈,SHIN DONG GUE,신동규,CHA JEONG DAN,차정단,CHO SANG MIN,조상민,JUNG JI HYE,정지혜
申请号：
KR1020180040062
公开号：
KR1020190117041A
申请日:
2018.04.06
申请国别(地区):
KR
年份:
2019
代理人:
摘要：
The present invention relates to an anti-inflammatory composition containing a fermented ginseng powder with increased content of ginsenoside Rg2. More specifically, the present invention relates to the anti-inflammatory composition containing the fermented ginseng powder which prepares the fermented ginseng powder with increased content of ginsenoside Rg2 by using probiotics and enzymes and has an anti-inflammatory effect through an effect of inhibiting nitric oxide (NO) production, an effect of inhibiting prostaglandin E2 (PGE2) production, an effect of inhibiting the expression of pro-inflammatory mediator enzymes, iNOS, COX-2, an effect of inhibiting the expression of inflammatory cytokines, TNF-α, IL-1β, and IL-6, and an effect of inhibiting the expression of NF-κB.본 발명은 Rg2 강화된 인삼발효분말을 함유하는 항염증 조성물에 관한 것이다. 더욱 상세하게는 프로바이오틱스와 효소를 이용하여 진세노사이드 Rg2가 강화된 인삼발효분말을 제조하고, NO(Nitric oxide) 생성 억제 효능, PGE2(Prostaglandin E2) 생성 억제 효능, 전구염증매개 효소 iNOS, COX-2 발현 억제 효능, 염증성 사이토카인 TNF-α, IL-1β 및 IL-6 발현 억제 효능 및 NF-κB 발현 억제효능을 통해 항염증 효능을 보유한 인삼발효분말을 포함하는 항염증 조성물에 관한 것이다.
