Arthur R.C. Braden,Jamboor K. Vishwanatha,Erica Kafka
申请号：
US14680505
公开号：
US20150209305A1
申请日:
2015.04.07
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention includes compositions and methods of making an activated polymeric nanoparticle for targeted drug delivery that includes a biocompatible polymer and an amphiphilic stabilizing agent non-covalently associated with a spacer compound that includes at least one electrophile that selectively reacts with any nucleophilic on a targeting agent and places the targeting agent on the exterior surface of a biodegradable nanoshell, wherein an active agent is loaded with the nanoshell.
